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Publications

Recent findings of scientific and clinical significance at the CVC are published below. Additional relevant literature by CVC staff may be found by the author's name at: www.pubmed.gov

Recent Publications:

View By Year: 2009 | 2008 | 2007 | 2006 | 2005

For publications prior to 2005, please contact us.

PlexinD1 Glycoprotein Controls Migration of Positively Selected Thymocytes into the Medulla. Immunity 29, 1-11.
Young I. Choi, Jonathan S. Duke-Cohan, Wesam B. Ahmed, Maris A. Handley, Fanny Mann, Jonathan A. Epstein, Linda K. Clayton, and Ellis L. Reinherz December 2008. View PDF (1) View PDF (2)
Data mining of cancer vaccine trials: a bird's-eye view. Immunome Res.4:7.
Cao X, Maloney KB, Brusic V. December 2008. View Web Site
Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment. Cancer Res. 68(21):8889-98.
Jinushi M, Nakazaki Y, Carrasco DR, Draganov D, Souders N, Johnson M, Mihm MC, Dranoff G. November 2008. View PDF
Cyclin D1-specific cytotoxic T lymphocytes are present in the repertoire of cancer patients: implications for cancer immunotherapy. Clin Cancer Res. 14(20):6574-9
Kondo E, Maecker B, Weihrauch MR,Wickenhauser C, Zeng W, Nadler LM, Schultze JL, von Bergwelt-Baildon MS October 2008. View Web Site
Cyclin D1-specific cytotoxic T lymphocytes are present in the repertoire of cancer patients: implications for cancer immunotherapy. Clin Cancer Res. 14(20):6574-9
Kondo E, Maecker B, Weihrauch MR, Wickenhauser C, Zeng W, Nadler LM, Schultze JL, von Bergwelt-Baildon MS October 2008. View Web Site
Stable long term donor engraftment following reduced intensity hematopoietic cell transplantation for sickle cell disease. Biol BMT (in press)
Krishnamurti L, Kharbanda S, Biernacki MA, Zhang W, Baker SB, Wagner JE and Wu CJ. October 2008.
Immunologic targeting of the cancer stem cell. The Stem Book (ed. L Girard).
Wu CJ. October 2008.
Comparative analysis of the expression patterns of various TNFSF/TNFRSF in atherosclerotic plaques. Immunol Invest. 37(4):359-73.
 Kim WJ, Kang YJ, Suk K, Park JE, Kwon BS, Lee WH. October 2008. View Web Site
Identification and characterization of conserved sequences of dengue virus proteins: implications for vaccine design. PLoS Neglected Tropical Diseases 2(8):e272.
Khan AM, Miotto O, Nascimento EJM, Srinivasan KN, Heiny AT, Zhang GL, Salmon J, Marques ET, Tan TW, Brusic V, August JT. August 2008. View Web Site
Critical technologies for bioinformatics. Briefings in Bioinformatics 9(4), 261-2.
Brusic V, Ranganathan S. July 2008.
Promiscuous T cell epitope prediction of Candida albicans secretory aspartyl proteinase family of proteins. Infection, Genetics and Evolution 8, 467-473.
Tongchusak S., Brusic V., Chaiyaroj S.C. July 2008. View Web Site
alpha-CTLA-4 mAb-associated Panenteritis: A Histologic and Immunohistochemical Analysis.Am J Surg Pathol.
Oble DA, Mino-Kenudson M, Goldsmith J, Hodi FS, Seliem RM, Dranoff G, Mihm M, Hasserjian R, Lauwers GY. June 2008. View Web Site
A concentration-dependent analysis method for high density protein microarrays. Journal of Proteome Research 7(5), 2059-68.
Marina O., Biernacki M., Brusic V., Wu C.J. May 2008. View Web Site
Double-blind randomized phase II study of the combination of sorafenib and dacarbazine in patients with advanced melanoma: a report from the 11715 Study Group. J Clin, 26(13):2178-85.
McDermott DF, Sosman JA, Gonzalez R, Hodi FS, Linette GP, Richards J, Jakub JW, Beeram M, Tarantolo S, Agarwala S, Frenette G, Puzanov I, Cranmer L, Lewis K, Kirkwood J, White JM, Xia C, Patel K, Hersh E. May 2008. View Web Site
PVS: a web server for protein sequence variability analysis tuned to facilitate conserved epitope discovery. Nucleic Acids Res.
Garcia-Boronat M, Diez-Rivero CM, Reinherz EL, Reche PA. April 2008. View Web Site
Major response to imatinib mesylate in KIT-mutated melanoma. J Clin Oncol, 26(12):2046-51.
Hodi FS, Friedlander P, Corless CL, Heinrich MC, Mac Rae S, Kruse A, Jagannathan J, Van den Abbeele AD, Velazquez EF, Demetri GD, Fisher DE. April 2008. View Web Site
Application of protein microarrays for multiplexed detection of antibodies to tumor antigens in breast cancer. J Proteome Res. 2008, 7(4):1490-9.
Anderson KS, Ramachandran N, Wong J, Raphael JV, Hainsworth E, Demirkan G, Cramer D, Aronzon D, Hodi FS, Harris L, Logvinenko T, LaBaer J. April 2008. View Web Site
In silico prediction and immunological validation of common HLA-DRB1-restricted T cell epitopes of Candida albicans secretory aspartyl proteinase 2. Microbiology and Immunology 52(4), 231-42.
Tongchusak S., Leelayuwat C., Brusic V., Chaiyaroj S.C. April 2008. View Web Site
Enhancing the clinical activity of granulocyte-macrophage colony-stimulating factor-secreting tumor cell vaccines. Immunol Rev, 222:287-98.
Jinushi M, Hodi FS, Dranoff G. April 2008. View Web Site
Application of protein microarrays for multiplexed detection of antibodies to tumor antigens in breast cancer. J Proteome Res, 7(4):1490-9.
Anderson KS, Ramachandran N, Wong J, Raphael JV, Hainsworth E, Demirkan G, Cramer D, Aronzon D, Hodi FS, Harris L, Logvinenko T, LaBaer J. April 2008. View Web Site
A prognostic score for patients with acute leukemia or myelodysplastic syndromes undergoing allogeneic stem cell transplantation. Biol Blood Marrow Transplant, 14, 28-35
Armand P, Kim HT, Cutler CS, Ho VT, Koreth J, Ritz J, Alyea EP, Antin JH, Soiffer RJ. April 2008. View Web Site
MHC class I chain-related protein A antibodies and shedding are involved in the progression of multiple myeloma. Proc Natl Acad Sci USA, 105, 1285-1290.
Jinushi M, Vanneman M, Munshi NC, Tai YT, Prabhala RH, Ritz J, Neuberg D, Anderson KC, Carrasco DR, Dranoff G. April 2008.
Capitalizing on the immunogenicity of dying tumor cells. Clin Cancer Res. 14(6):1603-8.
Fonseca C, Dranoff G. March 2008. View Web Site
Evaluation of MHC class I peptide binding prediction servers: applications for vaccine research. BMC Immunology 9:8.
Lin HH, Ray S, Tongchusak S, Reinherz EL, Brusic V. March 2008. View Web Site
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients. Proc Natl Acad Sci U S A., 105(8):3005-10.
Hodi FS, Butler M, Oble DA, Seiden MV, Haluska FG, Kruse A, Macrae S, Nelson M, Canning C, Lowy I, Korman A, Lautz D, Russell S, Jaklitsch MT, Ramaiya N, Chen TC, Neuberg D, Allison JP, Mihm MC, Dranoff G.
February 2008. View Web Site
Hotspot Hunter: a computational system for large-scale screening and selection of candidate immunological hotspots in pathogen proteomes. BMC Bioinformatics 9(Suppl. 1), S19.
Zhang GL, Khan AM, Srinivasan KN, Heiny AT, Lee KX, Kwoh CK, August JT, Brusic V February 2008. View PDF
Identification of human-to-human transmissibility factors in PB2 proteins of influenza A by large-scale mutual information analysis. BMC Bioinformatics 9(Suppl. 1), S18.
Miotto O, Heiny AT, Tan TW, August JT, Brusic V February 2008. View PDF
Rule-based knowledge aggregation for large-scale protein sequence analysis of influenza A viruses. BMC Bioinformatics 9(Suppl. 1), S7.
Miotto O, Tan TW, Brusic V February 2008. View PDF
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients, PNAS 105, 3005-3010.
Hodi FS, Butler M, Oble DA, Seiden MV, Haluska FG, Kruse A, MacRae S, Nelson M, Canning C, Lowy I, Korman A, Lautz D, Russell S, Jaklitsch MT, Ramaiya N, Chen TC, Neuberg D, Allison JP, Mihm MC, Dranoff G February 2008. View PDF
Inciting inflammation: the RAGE about tumor promotion. J Exp Med. 205(2):267-70.
Dougan M, Dranoff G. February 2008. View Web Site
Immunodominant-peptide recognition: beta testing TCRalphabeta. Immunity., 28(2):139-41.
Wang JH, Mallis RJ, Reinherz EL. February 2008.
Modeling genomic diversity and tumor dependency in malignant melanoma. Cancer Res., 68(3):664-73.
Lin WM, Baker AC, Beroukhim R, Winckler W, Feng W, Marmion JM, Laine E, Greulich H, Tseng H, Gates C, Hodi FS, Dranoff G, Sellers WR, Thomas RK, Meyerson M, Golub TR, Dummer R, Herlyn M, Getz G, Garraway LA. February 2008. View Web Site
MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma. Proc Natl Acad Sci U S A., 105(4):1285-90.
Jinushi M, Vanneman M, Munshi NC, Tai YT, Prabhala RH, Ritz J, Neuberg D, Anderson KC, Carrasco DR, Dranoff G. January 2008. View Web Site
A Novel H2A-E+ transgenic model susceptible to human but not mouse thyroglobulin-induced autoimmune thyroiditis: identification of mouse pathogenic epitopes. Cellular Immunology 51(1), 1-7.
Brown NK, McCormick DJ; BrusicV, David CS, Kong YC. January 2008. View Web Site
HIV-1 Broadly Neutralizing Antibody Extracts Its Epitope from a Kinked gp41 Ectodomain Region on the Viral Membrane. Immunity 28:52-63.
Sun ZY, Oh KJ, Kim M, Yu J, Brusic V, Song LK, Qiao Z, Wang JH, Wagner G, Reinherz EL. January 2008. View PDF (1) View PDF (2)
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Information for Patients

The CVC is developing new, disease-specific cancer vaccines by working closely with individual programs at DFCI.

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