Predicts MHC binding peptides from an input protein based on their similarity to a set of peptides known to bind to a given MHC molecule. Similarity is scored using Position Specific Scoring Matrixes (PSSM) derived from the aligned peptides known to bind to that MHC molecule.
Uses the Shannon Entropy function (H) to evaluate the sequence variability within a multiple sequence alignment. The sequence variability is then plotted against a selected sequence, and the regions with a variability under a given value sorted.
A tool designed to aid in the development of multi-epitope vaccines against pathogenic organisms based on genome-wide predictions of promiscous MHCI-restricted epitopes [Restricted Access].
Tools mirroed by Dr. Reche's
Immunomedicine Group
in the Facultad de Medicina de la Universidad Complutense de Madrid. SPAIN
